Microbes Infect. 2010 Jan 15. [Epub ahead of print]
Apicoplast: keep it or leave it
Fleige T, Limenitakis J, Soldati-Favre D.
Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 Rue Michel Servet, 1211 Geneva, Switzerland.
Most Apicomplexans possess a relic plastid named apicoplast, originating from secondary endosymbiosis of a red algae. This non-photosynthetic organelle fulfils important metabolic functions and confers sensitivity to antibiotics. The tasks of this organelle is compared across the phylum of Apicomplexa, highlighting its role in metabolic adaptation to different intracellular niches. Copyright © 2010. Published by Elsevier SAS.