Actin Nanobodies Uncover the Mystery of Actin Filament Dynamics in Toxoplasma gondii

Trends Parasitol. 2017 Jul 4. pii: S1471-4922(17)30156-3. doi: 10.1016/j.pt.2017.06.007. [Epub ahead of print]

Tardieux I¹.

While the intracellular parasite Toxoplasma relies on a divergent actomyosin motor to support unique speeds in directional movement, the dynamics and architecture of parasite actin filaments remain a much-discussed issue. Using actin chromobodies, Periz et al. started to unveil how networks of dynamic F-actin connect Toxoplasma progeny and expand in the replicative vacuole.

Copyright © 2017 Elsevier Ltd. All rights reserved.

PMID:

28687476

DOI:

10.1016/j.pt.2017.06.007