Recent developments in drug discovery against the protozoal parasites Cryptosporidium and Toxoplasma

Bioorg Med Chem Lett. 2017 Jan 17. pii: S0960-894X(17)30059-8. doi: 10.1016/j.bmcl.2017.01.046. [Epub ahead of print]

Chellan P¹, Sadler PJ¹, Land KM².

Apicomplexan parasites cause some of the most devastating human diseases, including malaria, toxoplasmosis, and cryptosporidiosis. New drug discovery is imperative in light of increased resistance. In this digest article, we briefly explore some of the recent and promising developments in new drug discovery against two apicomplexan parasites, Cryptosporidium and Toxoplasma.

Copyright © 2017 Elsevier Ltd. All rights reserved.

PMID:

28242275

DOI:

10.1016/j.bmcl.2017.01.046

[PubMed - as supplied by publisher]