Friday, April 24, 2015

Apicomplexan cell cycle flexibility: centrosome controls the clutch

 2015 Apr 19. pii: S1471-4922(15)00079-3. doi: 10.1016/j.pt.2015.04.003. [Epub ahead of print]

Chen CT1, Gubbels MJ2.

Abstract

The centrosome serves as a central hub coordinating multiple cellular events in eukaryotes. A recent study in Toxoplasma gondii revealed a unique bipartite structure of the centrosome, which coordinates the nuclear cycle (S-phase and mitosis) and budding cycle (cytokinesis) of the parasite, and deciphers the principle behind flexible apicomplexan cell division modes.
Copyright © 2015. Published by Elsevier Ltd.

KEYWORDS: 

Toxoplasma gondii; apicomplexa; centrosome; endodyogeny; schizogony
PMID:
 
25899747
 
[PubMed - as supplied by publisher]
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