Cell Microbiol. 2014 Feb 26. doi: 10.1111/cmi.12285. [Epub ahead of print]
The inner membrane complex through development of Toxoplasma gondii and Plasmodium
Abstract
Plasmodium spp and Toxoplasma gondii are important human and veterinary pathogens. These parasites possess an unusual double membrane structure located directly below the plasma membrane named the inner membrane complex (IMC). First identified in early electron micrograph studies, huge advances in genetic manipulation of the Apicomplexa have allowed the visualisation of a dynamic, highly structured cellular compartment with important roles in maintaining the structure and motility of these parasites. This review summarises recent advances in the field and highlights the changes the IMC undergoes during the complex life cycles of the Apicomplexa.
This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
- PMID:
- 24612102
- [PubMed - as supplied by publisher]
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