Wednesday, November 18, 2009

EuPathDB: a portal to eukaryotic pathogen databases

Nucleic Acids Res. 2009 Nov 13. [Epub ahead of print]

EuPathDB: a portal to eukaryotic pathogen databases

Aurrecoechea C, Brestelli J, Brunk BP, Fischer S, Gajria B, Gao X, Gingle A, Grant G, Harb OS, Heiges M, Innamorato F, Iodice J, Kissinger JC, Kraemer ET, Li W, Miller JA, Nayak V, Pennington C, Pinney DF, Roos DS, Ross C, Srinivasamoorthy G, Stoeckert CJ Jr, Thibodeau R, Treatman C, Wang H.

Center for Tropical & Emerging Global Diseases, University of Georgia, Athens, GA 30602, Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, Center for Applied Genetic Technologies, University of Georgia, Athens, GA 30602, Department of Genetics, University of Georgia, Athens, GA 30602 and Department of Computer Science, University of Georgia, Athens, GA 30602, USA.

EuPathDB (http://EuPathDB.org; formerly ApiDB) is an integrated database covering the eukaryotic pathogens of the genera Cryptosporidium, Giardia, Leishmania, Neospora, Plasmodium, Toxoplasma, Trichomonas and Trypanosoma. While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all these resources, and the opportunity to leverage orthology for searches across genera. The most recent release of EuPathDB includes updates and changes affecting data content, infrastructure and the user interface, improving data access and enhancing the user experience. EuPathDB currently supports more than 80 searches and the recently-implemented 'search strategy' system enables users to construct complex multi-step searches via a graphical interface. Search results are dynamically displayed as the strategy is constructed or modified, and can be downloaded, saved, revised, or shared with other database users.

PMID: 19914931 [PubMed - as supplied by publisher]

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