The Toxoplasma Blog

Up to date information and news regarding the protozoan parasite Toxoplasma gondii

Wednesday, September 27, 2017

Translational Control in the Latency of Apicomplexan Parasites

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Trends Parasitol. 2017 Sep 20. pii: S1471-4922(17)30211-8. doi: 10.1016/j.pt.2017.08.006. [Epub ahead of print] Holmes MJ 1 , Augusto ...
7 comments:

Apicomplexan actin polymerization depends on nucleation

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Sci Rep. 2017 Sep 22;7(1):12137. doi: 10.1038/s41598-017-11330-w. Kumpula EP 1 , Pires I 1 , Lasiwa D 1 , Piirainen H 1 , Bergmann U 1...
Friday, September 22, 2017

Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii

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J Med Chem. 2017 Sep 21. doi: 10.1021/acs.jmedchem.7b01192. [Epub ahead of print] Rutaganira FU , Barks J , Dhason MS , Wang Q , Lopez...
3 comments:
Thursday, September 21, 2017

Characterization of a cytoplasmic glucosyltransferase that extends the core trisaccharide of the Toxoplasma Skp1 E3 ubiquitin ligase subunit

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J Biol Chem. 2017 Sep 19. pii: jbc.M117.809301. doi: 10.1074/jbc.M117.809301. [Epub ahead of print] Rahman K 1 , Mandalasi M 1 , Zhao ...
2 comments:
Friday, September 15, 2017

NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes during Toxoplasma gondii Infection

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J Immunol. 2017 Sep 13. pii: ji1700245. doi: 10.4049/jimmunol.1700245. [Epub ahead of print] Gov L 1 , Schneider CA 1 , Lima TS 1 , Pa...

Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer

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Sci Rep. 2017 Sep 13;7(1):11496. doi: 10.1038/s41598-017-10675-6. Ngô HM 1, 2, 3 , Zhou Y 1 , Lorenzi H 4 , Wang K 5 , Kim TK 5 , Zho...
Thursday, September 14, 2017

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

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Elife.  2017 Sep 12;6. pii: e27480. doi: 10.7554/eLife.27480. Dogga SK 1 ,  Mukherjee B 1 ,  Jacot D 1 ,  Kockmann T 2 ,  Molino L 1 , ...

Influence of indigenous microbiota on experimental toxoplasmosis in conventional and germ-free mice

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Int J Exp Pathol.  2017 Sep 11. doi: 10.1111/iep.12236. [Epub ahead of print] Nascimento BB 1 ,  Cartelle CT 1 ,  Noviello ML 1 ,  Pinh...

IL17A-deficient mice are highly susceptible to Toxoplasma gondii infection due to excessively induced T. gondii HSP70 and IFN-γ production

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Infect Immun.  2017 Sep 11. pii: IAI.00399-17. doi: 10.1128/IAI.00399-17. [Epub ahead of print] Moroda M 1 ,  Takamoto M 2 ,  Iwakura Y...

Advances in the application of genetic manipulation methods to Apicomplexan parasites

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Int J Parasitol.  2017 Sep 8. pii: S0020-7519(17)30246-1. doi: 10.1016/j.ijpara.2017.08.002. [Epub ahead of print] Suarez CE 1 ,  Bisho...
Saturday, September 09, 2017

Toxoplasma gondii seroprevalence varies by cat breed

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PLoS One.  2017 Sep 8;12(9):e0184659. doi: 10.1371/journal.pone.0184659. eCollection 2017. Must K 1 ,  Hytönen MK 2, 3, 4 ,  Orro T 1 ,...

Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites

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Future Sci OA.  2017 May 12;3(3):FSO198. doi: 10.4155/fsoa-2017-0020. eCollection 2017 Aug. Galluzzi L 1 ,  Diotallevi A 1 ,  Magnani M...
Wednesday, September 06, 2017

Resistance towards monensin is proposed to be acquired in a Toxoplasma gondii model by reduced invasion and egress activities, in addition to increased intracellular replication

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Parasitology. 2017 Sep 5:1-13. doi: 10.1017/S0031182017001512. [Epub ahead of print] Thabet A 1 , Schmidt J 2 , Baumann S 2 , Honscha ...
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