PLoS Negl Trop Dis. 2014 May 29;8(5):e2908. doi: 10.1371/journal.pntd.0002908. eCollection 2014.
Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-saharan Africa
Kamuyu G1, Bottomley C2, Mageto J3, Lowe B4, Wilkins PP5, Noh JC5, Nutman TB6, Ngugi AK7, Odhiambo R8, Wagner RG9, Kakooza-Mwesige A10, Owusu-Agyei S11, Ae-Ngibise K11, Masanja H12, Osier FH8, Odermatt P13, Newton CR14; Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group.
BACKGROUND:Epilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE), in five sites across sub-Saharan Africa.
CONCLUSION:This study investigates how the degree of exposure to parasites and multiple parasitic infections are associated with ACE and may explain conflicting results obtained when only seropositivity is considered. The findings from this study should be further validated.
- [PubMed - in process]