Auton Neurosci. 2010 Feb 17. [Epub ahead of print]
Quantitative and morphometric changes of subpopulations of myenteric neurons in swines with toxoplasmosis
Odorizzi L, Moreira NM, Gonçalves GF, da Silva AV, Sant'ana DD, Araújo EJ.
Programa de Pós-Graduação em Ciência Animal, Universidade Paranaense, PR, Brazil.
The consequences of the infection caused by Toxoplasma gondii in myenteric neurons of the jejunum of swines reactive to NADH-diaphorase and NADPH-diaphorase were evaluated in this study. Ten 88-day-old mixed-breed swines (Pietrain and Wessex) were assigned into two groups: Control (n=5) and Experimental (n=5), which orally received 5000 sporulated oocysts from a genotype III T. gondii strain. After 30days, the animals were anesthetized, having part of their jejunum removed and stained with NADPH-diaphorase and NADH-diaphorase. NADPHd-p neurons (nitrergic) presented increase of the number of cells per ganglion and hypertrophy. The number of NADHd-p neurons (metabolic more active) and their nuclear area decreased. Copyright © 2010. Published by Elsevier B.V.
PMID: 20167543 [PubMed - as supplied by publisher]