Microbes Infect. 2007 Sep 14; [Epub ahead of print]
Cell-autonomous immunity to Toxoplasma gondii in mouse and man
Könen-Waisman S, Howard JC
Institute for Genetics, University of Cologne, Zülpicher Strasse 47, 50674 Cologne, Germany.
The protozoan, Toxoplasma gondii, is a natural pathogen of mouse and a zoonosis of man. Immunity against the pathogen is largely mediated by interferon-stimulated cell-autonomous mechanisms that are strikingly different between man and mouse. There are many poorly understood host and pathogen variables that affect the outcome of infection.
PMID: 18024121 [PubMed - as supplied by publisher]